1,2-Benzisoxazole-3-methanesulfonic acid sodium salt
Basic information
Product Name: 1,2-Benzisoxazole-3-methanesulfonic acid sodium salt
Synonyms:
CAS: 73101-64-1
MF: C8H8NNaO4S
MW: 237.2
Chemical Properties
Boiling Point: 275°C dec.
Density: Inert atmosphere,Room Temperature
storage temp: NA
Solubility: NA
Form: NA
Pka: NA
Color: NA
InChI: NA
InChIKey: NA
SMILES: NA
product description
Its uses are diverse, as follows:
As an Intermediate for Zonisamide: Sodium 1,2-benzisoxazole-3-methanesulfonate is a key intermediate in the synthesis of Zonisamide, an antiepileptic drug used to treat epilepsy by inhibiting the focus of seizures and blocking the spread of epileptic discharges.
Antiepileptic Drug: Zonisamide is used to treat epilepsy that is unresponsive to other medications, particularly partial seizures. It is effective against primary generalized seizures, mixed epilepsy, myoclonic seizures, and epilepsy syndromes such as Lennox-Gastaut syndrome and West syndrome, usually as an adjunct to other first-line drugs.
Pharmacological Action: Zonisamide has antiepileptic pharmacological effects by blocking voltage-sensitive sodium channels and reducing voltage-sensitive T-type calcium currents, thereby exhibiting antiepileptic effects.
Neuroprotective and Neuroresearch Products: Due to its antiepileptic properties, Sodium 1,2-benzisoxazole-3-methanesulfonate is also used in the field of neuroprotection and neuroresearch as a heterocyclic methanesulfonamide with antiepileptic characteristics.
Plant Tissue Culture: 1,2-Benzisoxazole-3-acetic acid (structurally similar to Sodium 1,2-benzisoxazole-3-methanesulfonate), as a new synthetic growth regulator, has been used in plant tissue culture, showing high activity especially during the plant regeneration stage of tobacco protoplasts.
These uses cover the applications of Sodium 1,2-benzisoxazole-3-methanesulfonate in the fields of medicine, plant tissue culture, and neuroscientific research, demonstrating its versatility in chemical and biological research.