![178554-19-3-2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl)--N,N-diMethylacetaMide.jpg](https://ecdn6-nc.globalso.com/upload/p/2809/image_product/2024-12/178554-19-3-2-1-2-1h-tetrazol-5-yl-1-1-biphenyl-4-yl-methyl-2-butyl-4-methyl-6-oxo-1-6-dihydropyrimidin-5-yl-n-n-dimethylacetamide.jpg)
![2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl)--N,N-diMethylacetaMide-178554-19-3.jpg](https://ecdn6-nc.globalso.com/upload/p/2809/image_product/2024-12/2-1-2-1h-tetrazol-5-yl-1-1-biphenyl-4-yl-methyl-2-butyl-4-methyl-6-oxo-1-6-dihydropyrimidin-5-yl-n-n-dimethylacetamide-178554-19-3.jpg)
2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl) -N,N-diMethylacetaMide
Basic information
Product Name: 2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl) -N,N-diMethylacetaMide
Synonyms:
CAS: 178554-19-3
MF: C27H31N7O2
MW: 485.58
Chemical Properties
Boiling Point: 705.9±70.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp: NA
Solubility: NA
Form: NA
Pka: 4.16±0.10(Predicted)
Color: NA
InChI: NA
InChIKey: NA
SMILES: NA
product description
As a highly selective URAT1 inhibitor, doltenolil does not affect the function of uric acid excretion factors ABCG2 and OAT1/3 compared with non-selective URAT1 inhibitors, so it has a higher blood uric acid lowering efficiency. Clinical studies have shown that doltenolaire is not inferior to benzbromarone or febuxostat in reducing serum uric acid levels in patients with hyperuricemia with or without gout, and does not weaken in patients with mild to moderate renal insufficiency or hepatic insufficiency. In long-term studies, most patients achieved a target serum uric acid level of ≤6 mg/dL at a maintenance dose of 2 or 4 mg once daily and were found to cause no safety concerns, including liver damage.
Doltenolaire should be stored in a dark, tightly sealed, and out of reach of children. Store at room temperature, i.e. in the range of 15-30 degrees Celsius, and avoid exposing the drug to extreme temperatures, such as too hot or too cold, so as not to compromise the effectiveness of the drug. In addition, doltenolil should be stored in a container protected from light to prevent direct sunlight from shining on the drug, as ultraviolet rays in sunlight may adversely affect the potency of the drug. Moisture has a detrimental effect on the stability of the drug, so moisture protection is another important factor in storing doltenolite, ensuring that the drug is stored in a dry place, away from water sources or humid environments.