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(3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester monohydrochloride

(3R,4R,5S)-4-N-acetyl(tert-butyl)amino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexen-1-carboxy-ethyl hydrochloride, also known as Ester chloromethyl carbonate (CMCE) or Ethyl 3-(tert-butoxycarbonylamino)-3-carboxy-1-(ethoxyimino)-5- Methyl-1-cyclohexanecarboxylate hydrochloride is an important pharmaceutical intermediate, mainly used for the synthesis of oseltamivir phosphate, that is, the phosphate form of oseltamivir. Oseltamivir is a neuraminidase inhibitor that is widely used for the treatment and prevention of influenza A and B.

    Basic information

    Product Name: (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester monohydrochloride
    Synonyms: 
    CAS: 651324-08-2
    MF: C26H45ClN2O4
    MW: 485.11

    Chemical Properties

    Boiling Point: NA
    Density: NA
    storage temp: under inert gas (nitrogen or Argon) at 2-8°C
    Solubility: NA
    Form: NA
    Pka: NA
    Color: NA
    InChI: NA
    InChIKey: NA
    SMILES: NA

    product description

    Quality:
    - Appearance: White solid
    Use:
    - It is used in scientific experiments to help scientists study the synthetic path and efficacy of drugs. Body.
    - The compound is a critical step in the synthesis of oseltamivir and is of great significance to the pharmaceutical industry.
    Method:
    - The synthesis method of CMCE is mainly by reacting the corresponding substrate with tert-butyl chloroformate (tert-butyl chloroformate) to obtain the desired compound.
    Safety Information:
    - CMCE is an intermediate in organic synthesis, which has certain toxicity to the human body, and is irritating and corrosive.
    - When using and handling CMCE, it is important to take appropriate precautions to avoid direct contact with the skin and eyes, and to ensure good ventilation.

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