5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride

Product Name: 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride

CAS: 720720-96-7

MF: C8H11ClN2O2S

MW: 234.7

Boiling Point: 175℃[at 101 325 Pa]

Density: NA

storage temp: under inert gas (nitrogen or Argon) at 2-8°C

Solubility: Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Very Slightly)

Form: Solid

Pka: NA

Color: Pale Beige to Light Brown

InChI: NA

InChIKey: NA

SMILES: NA

In terms of chemical properties, the compound has a molecular formula of C8H11ClN2O2S and a molecular weight of 234.7. It is a solid with a light beige to light brown color and hygroscopic properties with a melting point ranging from 199.0 to 203.0 °C and a boiling point of 175 °C. Storage conditions require storage at 2-8°C under an inert gas such as nitrogen or argon.

In terms of use, 5-methyl-4,5,6,7-tetrahydrothiazole[5,4-c]pyridine-2-carboxylate hydrochloride is mainly used as a reagent for the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclic methyl)thiophene-2-carboxamide derivatives as an antithrombotic agent. It can also be used as a reagent in the synthesis of diamide derivatives (FXa inhibitors). In particular, it is an intermediate of Edoxaban (E555520) and is used for drug declaration detection and as an impurity control substance.

In terms of solubility, the compound has some solubility in water (slightly soluble), DMSO (slightly soluble, heated, ultrasonic) and methanol (very slightly soluble). These properties make it an important application in the field of drug synthesis and pharmaceutical research.