Azure B

AzureB is a cationic dye (cationicdye), the main metabolite of Methyleneblue, which is used in Azure Eosin stain for blood smear staining. AzureB is a highly potent, selective and reversible inhibitor of monoamine oxidase (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. AzureB has significant antidepressant effects.

product details

Basic information

Product Name: Azure B

Synonyms:

CAS: 531-55-5

MF: C15H16ClN3S

MW: 305.82

Chemical Properties

Melting point: 205-210 °C (dec.)(lit.)

storage temp: -20°C Freezer

Solubility: H2O: soluble1mg/mL

Colour Index: 52010

Form: Powder

Color: Dark green

Water Solubility: Soluble

Λmax: 648–655 nm

Merck: 14,6058

BRN: 3922630

Stability: Stable. Incompatible with strong oxidizing agents.

Biological Applications:Antimalarial; biofuel cell; medical devices; diagnosis of amyloid accumulation related diseases,diabetes,malignant melanoma; detecting oral cancer,cells,nucleic acids; treating avian influenza virus,nail infection,oral cavity infection

InChIKey: DNDJEIWCTMMZBX-UHFFFAOYSA-N

CAS DataBase Reference: 531-55-5(CAS DataBase Reference)

product description

Biological Stain: Azure B is used for blood smear staining and in the preparation of azure eosin staining solution for blood smears.

Plant Tissue Staining: Used for semi-thin section staining of plant tissues and also for staining in the NCCLS method for blood smears and modified Lillie's Noct method for paraffin sections.

Nucleic Acid and Lignin Localization: Azure B is part of the Romanowsky staining used for blood smear staining and also for the localization of nucleic acids and lignin.

Medical Field Applications: Azure B has antimalarial effects and is used in biofuel cells, medical devices, diagnosis of diseases related to amyloid protein deposition, diabetes, malignant melanoma; detection of oral cancer, cells, nucleic acids; treatment of avian influenza virus, nail infections, oral infections, etc.

Chemical Synthesis: Azure B is an active metabolite in the preparation of azure eosin staining solution for blood smear staining.

In summary, Azure B (Methylthioninium chloride) with the CAS number 531-55-5 is a versatile compound, mainly used as a biological stain with a wide range of applications in the medical field. It is also valuable as a monoamine oxidase inhibitor in scientific research and medical studies. Proper safety measures should be followed during handling and storage to ensure safety and stability.