CARBINOXAMINE MALEATE SALT(CAS NO.:3505-38-2)
Basic information
Product Name: CARBINOXAMINE MALEATE SALT
Synonyms:
CAS: 3505-38-2
MF: C20H23ClN2O5
MW: 406.86
Chemical Properties
Melting point: 116-1180C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Water Solubility: Completely soluble in water
Solubility: Chloroform: Slightly Soluble; Methanol: Slightly Soluble
Form: Solid
Color: White to Almost white
Merck: 14,1799
InChI: Key GVNWHCVWDRNXAZ-BTJKTKAUSA-N
CAS DataBase Reference: 3505-38-2(CAS DataBase Reference)
EPA Substance Registry System: Ethanamine, 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethyl-, (2Z)-2-butenedioate (1:1) (3505-38-2)
product description
Allergic Rhinitis Treatment: The oral sustained-release suspension of Carbinoxamine Maleate, developed by Tris Pharma in the United States, is the first histamine receptor inhibitor for the treatment of seasonal and perennial allergic rhinitis in children over two years old. It was approved for marketing in the United States in 2013.
Antihistamine Medication: As a histamine H1-receptor antagonist, Carbinoxamine Maleate can block histamine H1 receptors, thereby reducing allergy symptoms.
Research and Chemical Reagents: Due to its special chemical properties, Carbinoxamine Maleate is also used in scientific research, chemical reagents, and foreign trade.
Drug Formulation Development: The preparation of Carbinoxamine Maleate sustained-release suspension involves ion exchange technology. This formulation has the characteristics of good liquidity, easy to take, easy to dose, and good taste masking, suitable for patients with difficulty swallowing.
Oral Long-Acting Formulations: The drug has a large and uniform distribution area in the gastrointestinal tract, low irritation, drug release is not affected by gastric emptying, and the drug release is stable with small individual differences.
Pharmaceutical Intermediates: Carbinoxamine Maleate is also used as a pharmaceutical intermediate for industrial production and material intermediates.