Flurbiprofen(CAS NO.:5104-49-4)
Basic information
Product Name: Flurbiprofen
Synonyms:
CAS: 5104-49-4
MF: C15H13FO2
MW: 244.26
Chemical Properties
Boiling Point: 376.2±30.0 °C(Predicted)
Density: 1.1795 (estimate)
storage temp: Sealed in dry,Room Temperature
Solubility: methanol: soluble50mg/mL
Form: White solid
Pka: pKa 3.80(H2O) (Uncertain)
Color: white to off-white
InChI: NA
InChIKey: SYTBZMRGLBWNTM-UHFFFAOYSA-N
SMILES: NA
product description
The physical and chemical properties of flurbiprofen include: the appearance is a white fine crystalline powder, the melting point is between 110-112 °C, soluble in ethanol, ether, acetone, chloroform and other organic solvents, almost insoluble in water, with a pungent odor. It has a boiling point of 376.2±30.0 °C (predicted), a density of 1.1795 (estimated), and a water solubility of 8 mg/L (room temperature).
In terms of safety, flurbiprofen has a hazard class of 6.1 (b) and belongs to the dangerous goods transport number UN 2811 6.1/PG 2, WGK Germany classification 3 and RTECS number DU8341000. Storage conditions: It is recommended to store tightly sealed at room temperature.
The preparation method of flurbiprofen includes the preparation of 2-fluorobiacetophenone through oxidation, esterification, transesterification, hydrolysis, decarboxylation and other reactions. As a non-selective cyclooxygenase (COX) inhibitor, flurbiprofen has a wide range of applications in the pharmaceutical field, especially in anti-inflammatory and pain management.