Products
CAS: 1314910-43-4
2-(azetidin-3-ylidene)acetonitrile (hydrochloride)
2-(3-Azetidinyl)acetonitrile hydrochloride (CAS number: 1314910-43-4) is an important pharmaceutical intermediate, primarily used in the synthesis of Baricitinib, a Janus kinase (JAK) inhibitor drug for the treatment of inflammatory diseases such as rheumatoid arthritis. This compound has the molecular formula C5H7ClN2 and a molecular weight of 130.58. It typically exists as a white solid and requires storage under inert gases (such as nitrogen or argon) at 2-8°C to maintain its stability. This compound has significant applications in the field of pharmaceutical manufacturing, especially in the research and development of new drugs and project submissions. Due to its key role in the synthesis of Baricitinib, 2-(3-Azetidinyl)acetonitrile hydrochloride is crucial for the development of effective treatment plans.
CAS: 1187595-85-2
2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonit...
1187595-85-2, also known as 2-[1-(ethylsulfonyl)-3-azetidinyl]acetonitrile, is an important organic synthetic intermediate primarily used in the synthesis of Baricitinib. Baricitinib is a Janus kinase (JAK) inhibitor drug used for the treatment of inflammatory diseases such as rheumatoid arthritis. This compound has the molecular formula C7H10N2O2S and a molecular weight of 186.23. It exists in a solid state, with a color ranging from grayish-white to light yellow, a melting point of 67-69°C, a boiling point of 360.8±52.0 °C (predicted), and a density of 1.33±0.1 g/cm3 (predicted). Storage conditions require sealing and storage at room temperature, and it is slightly soluble in DMSO and methanol. The acid dissociation constant (pKa) is -8.49±0.20 (predicted). In the pharmaceutical manufacturing field, 1187595-85-2 is particularly significant due to its application in the synthesis of Baricitinib, playing a crucial role in the development of effective treatment plans.
CAS: 1153949-11-1
1-Boc-3-(cyanomethylene)azetidine
3-(cyanomethylene)azabutane-1-carboxylate tert-butyl ester (CN, CAS number: 87674-68-8) is an organic compound.
CAS: 1146629-77-7
[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin...
[4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl valerate is a compound also known as ([4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate).
CAS: 1146629-76-6
[4-[1-(1-ethoxyethyl)-1H-pyrazol-4-yl]-7H-pyrro...
1146629-76-6, also known as Baricitinib Intermediate 1, is an important chemical intermediate primarily used in the synthesis of Baricitinib, a Janus kinase (JAK) inhibitor drug for the treatment of conditions such as rheumatoid arthritis. This compound has the molecular formula C19H25N5O3 with a molecular weight of 371.43 and exists in solid form, characterized by its specific chemical structure and physical properties. In the pharmaceutical manufacturing field, 1146629-76-6 plays a significant role as a key step in the synthesis of Baricitinib, which is crucial for developing effective treatment plans. Additionally, due to its application in the synthesis process, 1146629-76-6 is also considered as Baricitinib Impurity 64 and Baricitinib Impurity 67, indicating its role in drug quality control and research.
CAS: 1146629-75-5
(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methy...
(4-chloro-7H-pyrrolo[2,3-D]pyrimidin-7-yl)methyl tevurate. It is a white crystalline powder with low solubility.
It can also be used as a synthetic intermediate for pesticides, such as synthetic insecticides or herbicides.
CAS: 1029716-44-6
1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-...
1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxabora-2-yl)-1H-pyrazole, also known as TBPEP.