Products

2-(4-(2-chloroethyl)phenyl)-2-methylpropionic acid (CAS number: 2199440-16-7) is an organic compound, mainly as an intermediate of bilastine. Bilastine is a non-sedating long-acting histamine H1 receptor antagonist used to treat symptoms such as allergic rhinitis and chronic idiopathic urticaria. The compound has a molecular formula of C12H15ClO2 and a molecular weight of 226.7 and is a colorless to pale yellow crystalline solid. Bilastine exerts its therapeutic effect by selectively antagonizing peripheral H1 receptors with no affinity for muscarinic receptors. Indications include symptomatic treatment of urticaria in adults and adolescents 12 years of age and older, and bilastine can inhibit histamine-induced skin redness and herpes reaction for 24 hours after a single dose. In clinical studies, bilastine has demonstrated similar efficacy to levocetirizine, with a favorable safety profile and no major unexpected safety issues. The importance of this compound in pharmaceutical manufacturing is reflected in its contribution to the development of effective anti-allergy treatment options, particularly in providing non-sedative treatment options.

1-(2-Methoxyethyl)-2-(piperidin-4-yl)-1H-benzo[D]imidazole hydrochloride (CAS number: 1841081-72-8) is an organic compound that acts primarily as an impurity or intermediate of bilastine. Bilastine is a new, non-sedating H1 antihistamine used to treat symptoms such as allergic rhinitis and chronic idiopathic urticaria. The molecular formula of this compound is C16H24ClN3O, and the molecular weight is 309.83426. It needs to be stored in an inert gas atmosphere at room temperature when stored. Depending on its use, 1-(2-methoxyethyl)-2-(piperidin-4-yl)-1H-benzo[D]imidazole hydrochloride is a specific impurity of bilastine and is important for quality control in drug development, manufacturing, and regulatory submissions.

Methyl 2-(4-(2-chloroethyl)phenyl)-2-methylpropionate is an organic compound.

Tetra-tert-butyl4-(1H-benzo[D]imidazo-2-yl)piperidine-1-carboxylate is an organic compound.