The compound with CAS number 365998-36-3 is an edoxaban intermediate with the chemical name (5H-Pyrrolo[3,4-d]thiazole-5-carboxylic acid,2-[[[(1R,2S,5S)-2-[(5-chloro-1H-indol-2-yl)carbonyl]amino]-5-[(dimethylamino)carbonyl] cyclohexyl]amino]carbonyl]-4,6-dihydro-,1,1-dimethylethyl ester).This is an organic synthesis intermediate and pharmaceutical intermediate, which is mainly used in laboratory research and development processes and chemical and pharmaceutical synthesis processes, mainly as a synthetic intermediate of the API edoxaban. The intermediate has a solid powder, colorless or yellowish appearance, and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM). In terms of synthesis method, edoxaban intermediates are prepared by reacting 5H-Pyrrolo[3,4-d]thiazole-5-carboxylic acid with an appropriate activator to form activated esters, then reacting with specific amines to form intermediate compounds, and finally introducing 1,1-dimethylethyl ester groups through esterification reactions.
