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Triprolidine hydrochloride(CAS NO.:6138-79-0)

Triprolidine hydrochloride monohydrate (CAS number: 6138-79-0) is an orally active histamine H1 antagonist.

    Basic information

    Product Name: Triprolidine hydrochloride
    Synonyms: 
    CAS: 6138-79-0
    MF: C19H23ClN2
    MW: 314.85

    Chemical Properties

    Melting point: 115-120°C
    storage temp.: 2-8°C
    Solubility: alcohol: soluble1 in 1.5 of solvent
    Form: Solid
    Color: White to Off-White
    Water Solubility: >=10 g/100 mL at 20 ºC
    Merck: 13,9817
    Stability: Stable, but discolours in light. Incompatible with strong oxidizing agents.
    LogP: 4.223 (est)
    CAS DataBase Reference: 6138-79-0(CAS DataBase Reference)
    EPA Substance Registry System: Pyridine,2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride, monohydrate, (E)- (6138-79-0)

    product description

    Its uses are mainly reflected in the following aspects:
    1. Treatment of Allergic Rhinitis: Triprolidine hydrochloride monohydrate is used to treat allergic rhinitis, alleviating nasal symptoms caused by allergens.
    2. Treatment of Asthma: It is also used to treat asthma, helping to relieve asthma symptoms, especially in allergic asthma.
    3. Treatment of Urticaria and Skin Itching: Triprolidine hydrochloride monohydrate is also used to treat urticaria and allergic skin itching, reducing skin symptoms.
    4. Treatment of Allergic Conjunctivitis: In addition, it is used to treat allergic conjunctivitis, alleviating eye allergy symptoms.
    5. Research Purposes: Triprolidine hydrochloride monohydrate is also used in the field of scientific research, especially in studying the pathophysiological mechanisms of allergic diseases and the mechanisms of action of drugs.
    6. Spinal Motor and Sensory Blockade: In rats, triprolidine hydrochloride monohydrate can block spinal motor and sensation, indicating that it may have potential applications in neuroscience research.
    7. Drug Repurposing: It may also be used in drug repurposing studies to explore its potential role in the treatment of other diseases.
    In summary, the main uses of triprolidine hydrochloride monohydrate are concentrated in the treatment of allergic diseases and the field of scientific research, especially in allergic rhinitis, asthma, urticaria, skin itching, and allergic conjunctivitis. At the same time, it may also have applications in neuroscience research, especially in the study of spinal motor and sensory blockade.

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